← United States · Coverage record
US · SEC FORM 4
Xenon Pharmaceuticals Inc.
XENE · Nasdaq · CIK 0001582313 · Healthcare · Biotechnology
INSIDER SIGNAL
2 buyers · 2 purchase transaction lines · $1.7M gross purchase
WHY THIS SIGNAL?
Score anatomy
Each bar shows the contribution to the current score; the weights and formula stay unchanged.
What is holding the score back?
- ⚠ Cluster breadth is moderate · 2 insider(s), not 4+
- ⚠ Role scores low · most senior buyer: PRESIDENT & CEO (CEO, chair and 10% owners score lowest)
- ⚠ Buying conviction is reduced by concurrent selling
- ✓ Recent activity · latest purchase 2026-09-30
Purchase-size comments are relative to the model scale. Average daily volume is a separate market-context diagnostic.
US-v1.2 ranks qualifying equity purchases under the current 180-day rules. The score is a research priority, not a return forecast or probability. Backtests have not shown that a higher US score is followed by better returns.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
Showing the six most active owners; 4 additional owner(s) remain in Form 4 evidence.
Purchase breadth & concentration
Roles in the peak window: Chief Financial Officer, PRESIDENT & CEO. Concentration uses priced qualifying P lines only and does not change the saved score.
SIGNAL HISTORY
Latest recorded score
- 52.4
- 52.2
- 52.0
- 51.8
- 51.5
Only scores saved when a full US scoring run completed are shown; gaps are not reconstructed.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.
Price performance
- 1M
- -38.0%
- 3M
- -46.2%
- 6M
- -37.6%
- 12M
- -7.2%
Volatility & liquidity
- Volatility
- 57.1%
- Beta
- —
- Avg daily value
- USD 51.6M
Valuation
- Market cap
- —
- P/E
- —
Fundamentals
- Profit margin
- —
- ROE
- -59.5%
- Industry
- Biotechnology
Market data
Price data up to: 2026-10-11 · Price source: OpenBB/yfinance; volume from price cache (yfinance) · From SEC filings: ROE · Fiscal year ended: 2025-12-31 · Status: PASS
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 6,041,487
- Previous report
- 6,444,815
- Avg daily volume
- 3,834,835
- Days to cover
- 1.6
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-30 | MORTIMER IAN | Purchase (P) | Common Shares | 30,000 | USD 37.38 | USD 1,121,400 | SEC filing ↗ |
| 2026-09-30 | Kelly Thomas Patrick | Purchase (P) | Common Shares | 15,000 | USD 37.32 | USD 559,740 | SEC filing ↗ |
| 2022-01-21 | KENNEY CHRISTOPHER JOHN | Purchase (P) | Common Shares | 700 | USD 28.81 | USD 20,167 | SEC filing ↗ |
| 2021-12-06 | Von Seggern Christopher | Purchase (P) | Common Shares | 4,000 | USD 24.40 | USD 97,600 | SEC filing ↗ |
Form 4 evidence
51 transaction lines in the latest 365-day window; 241 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-10-15 | Kelly Thomas Patrick | Option exercise / conversion (M) | Common Shares | 7,500 | USD — | USD — | SEC filing ↗ |
| 2026-09-30 | MORTIMER IAN | Purchase (P) | Common Shares | 30,000 | USD 37.38 | USD 1,121,400 | SEC filing ↗ |
| 2026-09-30 | Kelly Thomas Patrick | Purchase (P) | Common Shares | 15,000 | USD 37.32 | USD 559,740 | SEC filing ↗ |
Show recent Form 4 evidence (30 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-10-15 | Kelly Thomas Patrick | Option exercise / conversion (M) | Common Shares | 7,500 | USD — | USD — | SEC filing ↗ |
| 2026-09-30 | MORTIMER IAN | Purchase (P) | Common Shares | 30,000 | USD 37.38 | USD 1,121,400 | SEC filing ↗ |
| 2026-09-30 | Kelly Thomas Patrick | Purchase (P) | Common Shares | 15,000 | USD 37.32 | USD 559,740 | SEC filing ↗ |
| 2026-09-01 | Svoronos Dawn | Option exercise / conversion (M) | Common Shares | 5,144 | USD 8.15 | USD 41,924 | SEC filing ↗ |
| 2026-08-28 | KENNEY CHRISTOPHER JOHN | Sale (S) | Common Shares | 7,068 | USD 60.25 | USD 425,849 | SEC filing ↗ |
| 2026-08-11 | GANNON STEVEN | Sale (S) | Common Shares | 10,000 | USD 64.06 | USD 640,600 | SEC filing ↗ |
| 2026-06-05 | PATOU GARY | Sale (S) | Common Shares | 1,322 | USD 53.14 | USD 70,251 | SEC filing ↗ |
| 2026-06-05 | Cannon Gillian | Sale (S) | Common Shares | 1,190 | USD 53.14 | USD 63,237 | SEC filing ↗ |
| 2026-06-01 | Svoronos Dawn | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | Svoronos Dawn | Tax withholding (F) | Common Shares | 1,416 | USD 53.41 | USD 75,629 | SEC filing ↗ |
| 2026-06-01 | PATOU GARY | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | Machado Patrick | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | Gover Justin D. | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | GAROFALO ELIZABETH A. | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | GANNON STEVEN | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-06-01 | GANNON STEVEN | Tax withholding (F) | Common Shares | 1,416 | USD 53.41 | USD 75,629 | SEC filing ↗ |
| 2026-06-01 | Cannon Gillian | Option exercise / conversion (M) | Common Shares | 2,645 | USD — | USD — | SEC filing ↗ |
| 2026-05-12 | GANNON STEVEN | Option exercise / conversion (M) | Common Shares | 3,500 | USD 7.38 | USD 25,830 | SEC filing ↗ |
| 2026-03-13 | MORTIMER IAN | Sale (S) | Common Shares | 7,308 | USD 55.23 | USD 403,621 | SEC filing ↗ |
| 2026-03-13 | KENNEY CHRISTOPHER JOHN | Sale (S) | Common Shares | 1,410 | USD 55.23 | USD 77,874 | SEC filing ↗ |
| 2026-03-13 | DiFabio Andrea | Sale (S) | Common Shares | 1,342 | USD 55.23 | USD 74,119 | SEC filing ↗ |
| 2026-03-12 | MORTIMER IAN | Option exercise / conversion (M) | Common Shares | 12,500 | USD — | USD — | SEC filing ↗ |
| 2026-03-12 | KENNEY CHRISTOPHER JOHN | Option exercise / conversion (M) | Common Shares | 3,750 | USD — | USD — | SEC filing ↗ |
| 2026-03-12 | DiFabio Andrea | Option exercise / conversion (M) | Common Shares | 3,750 | USD — | USD — | SEC filing ↗ |
| 2026-03-10 | MORTIMER IAN | Sale (S) | Common Shares | 11,269 | USD 60.11 | USD 677,380 | SEC filing ↗ |
| 2026-03-10 | KENNEY CHRISTOPHER JOHN | Sale (S) | Common Shares | 2,771 | USD 60.11 | USD 166,565 | SEC filing ↗ |
| 2026-03-10 | DiFabio Andrea | Sale (S) | Common Shares | 2,607 | USD 60.11 | USD 156,707 | SEC filing ↗ |
| 2026-03-09 | MORTIMER IAN | Sale (S) | Common Shares | 270,000 | USD 60.33 | USD 16,289,142 | SEC filing ↗ |
| 2026-03-09 | MORTIMER IAN | Option exercise / conversion (M) | Common Shares | 290,000 | USD — | USD — | SEC filing ↗ |
| 2026-03-09 | KENNEY CHRISTOPHER JOHN | Option exercise / conversion (M) | Common Shares | 7,500 | USD — | USD — | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-18 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | XENE |
| CIK | 0001582313 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 241 transaction lines from 2020-05-26 to 2026-10-15 4 P purchase lines · 106 S sale lines · 131 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.