← United States · Coverage record
US · SEC FORM 4
AGIOS PHARMACEUTICALS, INC.
AGIO · Nasdaq · CIK 0001439222 · Healthcare · Biotechnology
INSIDER SIGNAL
0 qualifying P purchase groups
in the current 180-day scoring window
14 Form 4 transaction lines observed in the same window
2 sales · 12 option, withholding, award, gift or other lines
WHY NO ACTIVE SIGNAL?
Score anatomy
No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.
Why is there no score?
- No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
- Sales and other Form 4 activity remain visible as context and do not create a negative score.
Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
Showing the six most active owners; 4 additional owner(s) remain in Form 4 evidence.
Purchase breadth, concentration & cluster buying
These modules activate when qualifying purchases enter the 180-day research window.
SIGNAL HISTORY
Scores are archived only when the company qualifies for a published US buy-signal snapshot.—
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.
Price performance
- 1M
- -4.2%
- 3M
- -25.8%
- 6M
- -9.7%
- 12M
- -21.7%
Volatility & liquidity
- Volatility
- 66.0%
- Beta
- 0.63
- Avg daily value
- USD 34.1M
Valuation
- Market cap
- USD 1.9B
- P/E
- —
Fundamentals
- Profit margin
- -764.4%
- ROE
- -34.6%
- Industry
- Biotechnology
Market data
Price data up to: 2026-10-06 · Price source: OpenBB/yfinance · From SEC filings: Profit margin, ROE · Fiscal year ended: 2025-12-31 · From Yahoo Finance: Market cap · Status: PASS
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 7,016,166
- Previous report
- 7,557,252
- Avg daily volume
- 1,089,910
- Days to cover
- 6.4
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
No qualifying code P equity purchase is present in the local Form 4 history.
Form 4 evidence
87 transaction lines in the latest 365-day window; 496 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-08-04 | Gheuens Sarah | Sale (S) | Common stock | 30,000 | USD 30.48 | USD 914,400 | SEC filing ↗ |
| 2026-07-08 | Backstrom Jay T. | Award / grant (A) | Common stock | 1,447 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-07-01 | Gheuens Sarah | Sale (S) | Common stock | 4,007 | USD 37.56 | USD 150,503 | SEC filing ↗ |
Show recent Form 4 evidence (30 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-08-04 | Gheuens Sarah | Sale (S) | Common stock | 30,000 | USD 30.48 | USD 914,400 | SEC filing ↗ |
| 2026-07-08 | Backstrom Jay T. | Award / grant (A) | Common stock | 1,447 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-07-01 | Gheuens Sarah | Sale (S) | Common stock | 4,007 | USD 37.56 | USD 150,503 | SEC filing ↗ |
| 2026-07-01 | Gheuens Sarah | Option exercise / conversion (M) | Common stock | 8,375 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Smith Cynthia | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Scadden David | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Owen Adams Catherine | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Ho Maykin | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Foster-Cheek Kaye I | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | FOUSE JACQUALYN A | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | CAPELLO JEFFREY D | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-18 | Ballal Rahul D. | Option exercise / conversion (M) | Common stock | 2,816 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-13 | Owen Adams Catherine | Option exercise / conversion (M) | Common stock | 1,976 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-06-13 | CAPELLO JEFFREY D | Option exercise / conversion (M) | Common stock | 1,976 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Viswanadhan Krishnan | Sale (S) | Common stock | 2,959 | USD 34.71 | USD 102,707 | SEC filing ↗ |
| 2026-04-02 | Viswanadhan Krishnan | Option exercise / conversion (M) | Common stock | 8,100 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Milanova Tsveta | Sale (S) | Common stock | 3,262 | USD 34.71 | USD 113,224 | SEC filing ↗ |
| 2026-04-02 | Milanova Tsveta | Option exercise / conversion (M) | Common stock | 8,500 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Jones Cecilia | Sale (S) | Common stock | 3,141 | USD 34.71 | USD 109,024 | SEC filing ↗ |
| 2026-04-02 | Jones Cecilia | Option exercise / conversion (M) | Common stock | 8,500 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Goff Brian | Sale (S) | Common stock | 19,068 | USD 34.71 | USD 661,850 | SEC filing ↗ |
| 2026-04-02 | Goff Brian | Option exercise / conversion (M) | Common stock | 39,028 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Gheuens Sarah | Sale (S) | Common stock | 2,940 | USD 34.71 | USD 102,047 | SEC filing ↗ |
| 2026-04-02 | Gheuens Sarah | Option exercise / conversion (M) | Common stock | 8,500 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-02 | Burns James William | Sale (S) | Common stock | 3,280 | USD 34.71 | USD 113,849 | SEC filing ↗ |
| 2026-04-02 | Burns James William | Option exercise / conversion (M) | Common stock | 8,500 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-03-05 | Viswanadhan Krishnan | Sale (S) | Common stock | 2,959 | USD 27.80 | USD 82,260 | SEC filing ↗ |
| 2026-03-05 | Viswanadhan Krishnan | Option exercise / conversion (M) | Common stock | 8,100 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-03-03 | Washburn Theodore James Jr. | Sale (S) | Common stock | 5,272 | USD 28.88 | USD 152,255 | SEC filing ↗ |
| 2026-03-02 | Washburn Theodore James Jr. | Sale (S) | Common stock | 2,223 | USD 28.96 | USD 64,378 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-18 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | AGIO |
| CIK | 0001439222 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 496 transaction lines from 2020-02-04 to 2026-08-04 0 P purchase lines · 169 S sale lines · 327 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.