Stock Trading Canary

United States · SEC Form 4 · Snapshot date: 2026-10-18 · Built: 2026-10-18 · 中文

← United States · Coverage record

US · SEC FORM 4

ANAPTYSBIO, INC

ANAB · Nasdaq · CIK 0001370053 · Healthcare · Biotechnology

INSIDER SIGNAL

No active buy signal

0 qualifying P purchase groups
in the current 180-day scoring window

6 Form 4 transaction lines observed in the same window
1 sales · 5 option, withholding, award, gift or other lines

Last qualifying purchase2025-01-02 · EcoR1 Capital, LLC; NODELMAN OLEG · $86.1K

WHY NO ACTIVE SIGNAL?

Purchase activityNone
Recent buyingNone
Recent salesLow
Buy signal statusInactive
Score anatomy

No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.

ClusterNot calculated
Purchase sizeNot calculated
RoleNot calculated
RecencyNot calculated
ConvictionNot calculated

Why is there no score?

  • No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
  • Sales and other Form 4 activity remain visible as context and do not create a negative score.

Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.

Insider activity timeline

Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.

AprMayJunJulAugSepOct
RENTON HOLLINGSDirector
○○▼
Orwin John ADirector
○○
Schmid John P.Director
○
● Purchase▼ Sale○ Other

—

Purchase breadth, concentration & cluster buying

These modules activate when qualifying purchases enter the 180-day research window.

SIGNAL HISTORY

No recorded active-signal snapshot

Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2025-01-02 · EcoR1 Capital, LLC; NODELMAN OLEG.

Recent Form 4 activity

0Purchases
39Sales
28Other Form 4 lines
27SEC filings · 365 days
BUYING0 qualifying P line(s) · 180 days
SELLING1 sale line(s) · context only
OTHER5 exercise / withholding / award / gift / other lines
10b5-1 / PLANNEDNot assessed

P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.

Market context

Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.

Price performance

1M
-13.1%
3M
-22.1%
6M
+26.2%
12M
—

Volatility & liquidity

Volatility
62.7%
Beta
0.41
Avg daily value
USD 27.9M

Valuation

Market cap
USD 1.5B
P/E
—

Fundamentals

Profit margin
-5.6%
ROE
-35.6%
Industry
Biotechnology

Market data

Price data up to: 2026-10-03 · Price source: OpenBB/yfinance · From SEC filings: Profit margin, ROE · Fiscal year ended: 2025-12-31 · From Yahoo Finance: Market cap · Status: PASS

Short interest

Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.

Shares short
5,236,151
Previous report
5,437,438
Avg daily volume
639,524
Days to cover
8.2

FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.

Historical equity purchases

Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.

Transaction dateReporting ownerTypeSecuritySharesAvg. priceApprox. valueSource
2025-01-02EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock6,646USD 12.95USD 86,066SEC filing ↗
2024-12-31EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock13,268USD 12.93USD 171,555SEC filing ↗
2024-12-30EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock65,184USD 12.92USD 842,177SEC filing ↗
2024-08-14EcoR1 Capital, LLCPurchase (P)Common Stock273,972USD 36.50USD 9,999,978SEC filing ↗
2022-05-05EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock668,237USD 21.63USD 14,453,966SEC filing ↗
2021-05-04EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock165,000USD 23.25USD 3,836,250SEC filing ↗
2021-05-03EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock20,800USD 23.31USD 484,848SEC filing ↗
2021-04-30EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock35,700USD 23.16USD 826,812SEC filing ↗
2021-04-27EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock33,800USD 23.82USD 805,116SEC filing ↗
2021-04-26EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock13,900USD 23.80USD 330,820SEC filing ↗
2021-04-23EcoR1 Capital, LLC; NODELMAN OLEGPurchase (P)Common Stock99,600USD 23.54USD 2,344,584SEC filing ↗
2021-03-09EcoR1 Capital, LLCPurchase (P)Common Stock531,000USD 18.70USD 9,929,700SEC filing ↗
2021-03-08EcoR1 Capital, LLCPurchase (P)Common Stock2,777,800USD 18.97USD 52,694,866SEC filing ↗
2021-02-23EcoR1 Capital, LLCPurchase (P)Common Stock29,500USD 25.48USD 751,660SEC filing ↗

Form 4 evidence

67 transaction lines in the latest 365-day window; 211 in local history.

DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-10-01RENTON HOLLINGSSale (S)Common Stock5,000USD 49.87USD 249,372SEC filing ↗
2026-10-01RENTON HOLLINGSOption exercise / conversion (M)Common Stock5,000USD 18.03USD 90,150SEC filing ↗
2026-09-15Orwin John AOption exercise / conversion (M)Common Stock1,300USD 0.00USD 0SEC filing ↗
Show recent Form 4 evidence (30 grouped rows)
DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-10-01RENTON HOLLINGSSale (S)Common Stock5,000USD 49.87USD 249,372SEC filing ↗
2026-10-01RENTON HOLLINGSOption exercise / conversion (M)Common Stock5,000USD 18.03USD 90,150SEC filing ↗
2026-09-15Orwin John AOption exercise / conversion (M)Common Stock1,300USD 0.00USD 0SEC filing ↗
2026-06-15Schmid John P.Option exercise / conversion (M)Common Stock6,030USD 0.00USD 0SEC filing ↗
2026-06-15RENTON HOLLINGSOption exercise / conversion (M)Common Stock6,030USD 0.00USD 0SEC filing ↗
2026-06-15Orwin John AOption exercise / conversion (M)Common Stock6,030USD 0.00USD 0SEC filing ↗
2026-03-27Faga DanielSale (S)Common Stock17,679USD 61.61USD 1,089,222SEC filing ↗
2026-03-25Faga DanielAward / grant (A)Common Stock34,300USD —USD —SEC filing ↗
2026-02-11LOUMEAU ERIC JSale (S)Common Stock10,000USD 54.00USD 540,000SEC filing ↗
2026-02-11LOUMEAU ERIC JOption exercise / conversion (M)Common Stock10,000USD 29.70USD 297,000SEC filing ↗
2026-01-15Marquet MagdaSale (S)Common Stock11,000USD 48.23USD 530,568SEC filing ↗
2026-01-15Marquet MagdaOption exercise / conversion (M)Common Stock11,000USD 26.11USD 287,210SEC filing ↗
2026-01-08MULROY DENNISSale (S)Common Stock2,515USD 44.71USD 112,446SEC filing ↗
2026-01-08Lizzul Paul F.Sale (S)Common Stock3,650USD 44.71USD 163,192SEC filing ↗
2026-01-08LOUMEAU ERIC JSale (S)Common Stock2,210USD 44.71USD 98,809SEC filing ↗
2026-01-08Faga DanielSale (S)Common Stock14,281USD 44.71USD 638,504SEC filing ↗
2026-01-07MULROY DENNISOption exercise / conversion (M)Common Stock6,700USD —USD —SEC filing ↗
2026-01-07Lizzul Paul F.Option exercise / conversion (M)Common Stock8,525USD —USD —SEC filing ↗
2026-01-07LOUMEAU ERIC JOption exercise / conversion (M)Common Stock5,888USD —USD —SEC filing ↗
2026-01-07Faga DanielOption exercise / conversion (M)Common Stock26,838USD —USD —SEC filing ↗
2026-01-07MULROY DENNISSale (S)Common Stock1,908USD 45.11USD 86,070SEC filing ↗
2026-01-07Lizzul Paul F.Sale (S)Common Stock2,235USD 45.11USD 100,821SEC filing ↗
2026-01-07LOUMEAU ERIC JSale (S)Common Stock9,639USD 45.56USD 439,179SEC filing ↗
2026-01-07Faga DanielSale (S)Common Stock9,202USD 45.11USD 415,102SEC filing ↗
2026-01-06MULROY DENNISOption exercise / conversion (M)Common Stock5,245USD —USD —SEC filing ↗
2026-01-06Lizzul Paul F.Option exercise / conversion (M)Common Stock6,145USD —USD —SEC filing ↗
2026-01-06LOUMEAU ERIC JOption exercise / conversion (M)Common Stock5,545USD —USD —SEC filing ↗
2026-01-06Faga DanielOption exercise / conversion (M)Common Stock17,850USD —USD —SEC filing ↗
2026-01-05MULROY DENNISSale (S)Common Stock3,363USD 43.26USD 145,483SEC filing ↗
2026-01-05Lizzul Paul F.Sale (S)Common Stock4,219USD 43.26USD 182,514SEC filing ↗

Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.

Snapshot & identity

Snapshot date2026-10-18
Ranking versionUS-v1.2
Data qualityPASS ELIGIBLE · —
TickerANAB
CIK0001370053
SectorHealthcare
IndustryBiotechnology Yahoo Finance
SEC SIC2834 Pharmaceutical Preparations
ExchangeNasdaq

Data coverage

Local Form 4 history211 transaction lines from 2020-02-05 to 2026-10-01
14 P purchase lines · 89 S sale lines · 108 other lines
SEC company submissionsOpen SEC filings ↗

Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.