Stock Trading Canary

United States · SEC Form 4 · Snapshot date: 2026-10-18 · Built: 2026-10-18 · 中文

← United States · Coverage record

US · SEC FORM 4

Annovis Bio, Inc.

ANVS · NYSE · CIK 0001477845 · Healthcare · Biotechnology

INSIDER SIGNAL

46.7 / 100

1 buyers · 3 purchase transaction lines · $142.8K gross purchase

WHY THIS SIGNAL?

Buyer breadthLow
Purchase sizeLow
RoleStrong
RecencyLow
ConvictionStrong
Score anatomy

Each bar shows the contribution to the current score; the weights and formula stay unchanged.

Cluster+7.0 / 35
Purchase size+8.9 / 25
Role+20.0 / 20
Recency+0.8 / 10
Conviction+10.0 / 10

What is holding the score back?

  • ⚠ Cluster breadth is moderate · 1 insider(s), not 4+
  • ⚠ Purchase size is modest relative to the model scale
  • ⚠ Purchase activity is becoming less recent
  • ✓ Role scores high · most senior buyer: Director

Purchase-size comments are relative to the model scale. Average daily volume is a separate market-context diagnostic.

US-v1.2 ranks qualifying equity purchases under the current 180-day rules. The score is a research priority, not a return forecast or probability. Backtests have not shown that a higher US score is followed by better returns.

Insider activity timeline

Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.

AprMayJunJulAugSepOct
Hoffman Michael BDirector
●
● Purchase▼ Sale○ Other

—

Purchase breadth & concentration

QUALIFYING BUYERS1
PURCHASE CONCENTRATION100%Largest buyer: Hoffman Michael B · $142.8K
CLUSTER BUYING · 15D1 insiderPeak activity: 2026-05-20–2026-05-20

Roles in the peak window: Director. Concentration uses priced qualifying P lines only and does not change the saved score.

SIGNAL HISTORY

46.7 / 100

Latest recorded score

↓ -0.1 ptsversus the previous recorded snapshot
  1. 46.9
  2. 46.8
  3. 46.8
  4. 46.8
  5. 46.7

Only scores saved when a full US scoring run completed are shown; gaps are not reconstructed.

Recent Form 4 activity

19Purchases
0Sales
0Other Form 4 lines
9SEC filings · 365 days
BUYING3 qualifying P line(s) · 180 days
SELLING0 sale line(s) · context only
OTHER0 exercise / withholding / award / gift / other lines
10b5-1 / PLANNEDNot assessed

P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.

Market context

Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.

Price performance

1M
+1.7%
3M
-31.2%
6M
-23.9%
12M
-46.7%

Volatility & liquidity

Volatility
94.2%
Beta
—
Avg daily value
USD 1.1M

Valuation

Market cap
USD 51.6M
P/E
—

Fundamentals

Profit margin
—
ROE
-171.2%
Industry
Biotechnology

Market data

Price data up to: 2026-10-11 · Price source: OpenBB/yfinance; volume from price cache (yfinance) · From SEC filings: Market cap, ROE · Fiscal year ended: 2025-12-31 · Market cap is the shares outstanding stated on the filing cover multiplied by the latest close. Share count date: 2026-08-14 · Status: PASS

Short interest

Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.

Shares short
5,895,922
Previous report
6,022,040
Avg daily volume
990,573
Days to cover
6.0

FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.

Historical equity purchases

Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.

Transaction dateReporting ownerTypeSecuritySharesAvg. priceApprox. valueSource
2026-05-20Hoffman Michael BPurchase (P)Common Stock76,344USD 1.87USD 142,784SEC filing ↗
2026-04-02Hoffman Michael BPurchase (P)Common Stock713,800USD 2.10USD 1,498,980SEC filing ↗
2025-12-08Hoffman Michael BPurchase (P)Common Stock45,000USD 4.31USD 193,800SEC filing ↗
2025-11-24Hoffman Michael BPurchase (P)Common Stock39,200USD 4.08USD 159,886SEC filing ↗
2025-11-24Hoffman Michael BPurchase (P)Common Stock39,200USD 4.08USD 159,886SEC filing ↗
2025-11-21Hoffman Michael BPurchase (P)Common Stock20,000USD 3.50USD 69,900SEC filing ↗
2025-11-14Hoffman Michael BPurchase (P)Common Stock15,000USD 2.11USD 31,650SEC filing ↗
2025-10-28Maccecchini Maria-LuisaPurchase (P)Common Stock97,561USD 2.05USD 200,000SEC filing ↗
2025-10-28Hoffman Michael BPurchase (P)Common Stock975,610USD 2.05USD 2,000,000SEC filing ↗
2021-10-12White Mark K.Purchase (P)Common Stock5,000USD 27.40USD 137,000SEC filing ↗
2021-10-11Maccecchini Maria-LuisaPurchase (P)Common Stock18,000USD 27.61USD 496,980SEC filing ↗
2021-10-11Bruck ClaudinePurchase (P)Common Stock181USD 27.66USD 5,006SEC filing ↗
2021-08-19McCarthy ReidPurchase (P)Common Stock, $0.0001 par value500USD 37.61USD 18,805SEC filing ↗
2020-02-03McGroarty Jeffrey BrianPurchase (P)Common Stock19,500USD 7.15USD 139,428SEC filing ↗
2020-01-31White Mark K.Purchase (P)Common Stock1,734USD 6.00USD 10,404SEC filing ↗

Form 4 evidence

19 transaction lines in the latest 365-day window; 88 in local history.

DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-05-20Hoffman Michael BPurchase (P)Common Stock76,344USD 1.87USD 142,784SEC filing ↗
2026-04-02Hoffman Michael BPurchase (P)Common Stock713,800USD 2.10USD 1,498,980SEC filing ↗
2025-12-08Hoffman Michael BPurchase (P)Common Stock45,000USD 4.31USD 193,800SEC filing ↗
Show recent Form 4 evidence (9 grouped rows)
DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-05-20Hoffman Michael BPurchase (P)Common Stock76,344USD 1.87USD 142,784SEC filing ↗
2026-04-02Hoffman Michael BPurchase (P)Common Stock713,800USD 2.10USD 1,498,980SEC filing ↗
2025-12-08Hoffman Michael BPurchase (P)Common Stock45,000USD 4.31USD 193,800SEC filing ↗
2025-11-24Hoffman Michael BPurchase (P)Common Stock39,200USD 4.08USD 159,886SEC filing ↗
2025-11-24Hoffman Michael BPurchase (P)Common Stock39,200USD 4.08USD 159,886SEC filing ↗
2025-11-21Hoffman Michael BPurchase (P)Common Stock20,000USD 3.50USD 69,900SEC filing ↗
2025-11-14Hoffman Michael BPurchase (P)Common Stock15,000USD 2.11USD 31,650SEC filing ↗
2025-10-28Maccecchini Maria-LuisaPurchase (P)Common Stock97,561USD 2.05USD 200,000SEC filing ↗
2025-10-28Hoffman Michael BPurchase (P)Common Stock975,610USD 2.05USD 2,000,000SEC filing ↗

Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.

Snapshot & identity

Snapshot date2026-10-18
Ranking versionUS-v1.2
Data qualityPASS ELIGIBLE · —
TickerANVS
CIK0001477845
SectorHealthcare
IndustryBiotechnology Yahoo Finance
SEC SIC2834 Pharmaceutical Preparations
ExchangeNYSE

Data coverage

Local Form 4 history88 transaction lines from 2020-01-31 to 2026-05-20
31 P purchase lines · 0 S sale lines · 57 other lines
SEC company submissionsOpen SEC filings ↗

Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.