← United States · Coverage record
US · SEC FORM 4
ARROWHEAD PHARMACEUTICALS, INC.
ARWR · Nasdaq · CIK 0000879407 · Healthcare · Biotechnology
INSIDER SIGNAL
0 qualifying P purchase groups
in the current 180-day scoring window
8 Form 4 transaction lines observed in the same window
7 sales · 1 option, withholding, award, gift or other lines
WHY NO ACTIVE SIGNAL?
Score anatomy
No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.
Why is there no score?
- No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
- Sales and other Form 4 activity remain visible as context and do not create a negative score.
Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
—
Purchase breadth, concentration & cluster buying
These modules activate when qualifying purchases enter the 180-day research window.
SIGNAL HISTORY
Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2024-04-18 · Lu Hongbo.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.
Price performance
- 1M
- -27.8%
- 3M
- -26.8%
- 6M
- -4.5%
- 12M
- +63.9%
Volatility & liquidity
- Volatility
- 67.1%
- Beta
- —
- Avg daily value
- USD 117.4M
Valuation
- Market cap
- —
- P/E
- —
Fundamentals
- Profit margin
- -0.2%
- ROE
- -0.3%
- Industry
- Biotechnology
Market data
Price data up to: 2026-10-07 · Price source: OpenBB/yfinance; volume from price cache (yfinance) · From SEC filings: Profit margin, ROE · Fiscal year ended: 2025-09-30 · Status: PASS
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 10,760,463
- Previous report
- 9,272,290
- Avg daily volume
- 2,669,000
- Days to cover
- 4.0
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2024-04-18 | Lu Hongbo | Purchase (P) | Common Stock | 500 | USD 22.00 | USD 11,000 | SEC filing ↗ |
| 2024-04-10 | Lu Hongbo | Purchase (P) | Common Stock | 500 | USD 25.00 | USD 12,500 | SEC filing ↗ |
| 2024-04-02 | Lu Hongbo | Purchase (P) | Common Stock | 150 | USD 27.34 | USD 4,101 | SEC filing ↗ |
| 2024-03-26 | Lu Hongbo | Purchase (P) | Common Stock | 850 | USD 27.50 | USD 23,375 | SEC filing ↗ |
| 2024-03-22 | Lu Hongbo | Purchase (P) | Common Stock | 400 | USD 28.00 | USD 11,200 | SEC filing ↗ |
| 2024-03-20 | Lu Hongbo | Purchase (P) | Common Stock | 1,000 | USD 27.50 | USD 27,500 | SEC filing ↗ |
| 2024-03-19 | Lu Hongbo | Purchase (P) | Common Stock | 1,000 | USD 28.00 | USD 28,000 | SEC filing ↗ |
| 2024-03-18 | Lu Hongbo | Purchase (P) | Common Stock | 1,000 | USD 27.49 | USD 27,490 | SEC filing ↗ |
| 2021-12-28 | GIVEN DOUGLAS B | Purchase (P) | Common Stock | 655 | USD 66.37 | USD 43,472 | SEC filing ↗ |
| 2020-10-08 | De Backer Marianne | Purchase (P) | Common Stock | 1,000 | USD 50.47 | USD 50,465 | SEC filing ↗ |
| 2020-06-15 | De Backer Marianne | Purchase (P) | Common Stock | 500 | USD 31.33 | USD 15,665 | SEC filing ↗ |
| 2020-04-15 | De Backer Marianne | Purchase (P) | Common Stock | 500 | USD 35.40 | USD 17,700 | SEC filing ↗ |
| 2020-03-16 | De Backer Marianne | Purchase (P) | Common Stock | 500 | USD 23.94 | USD 11,970 | SEC filing ↗ |
| 2020-03-12 | De Backer Marianne | Purchase (P) | Common Stock | 500 | USD 24.80 | USD 12,400 | SEC filing ↗ |
| 2020-03-11 | De Backer Marianne | Purchase (P) | Common Stock | 500 | USD 28.60 | USD 14,300 | SEC filing ↗ |
Form 4 evidence
81 transaction lines in the latest 365-day window; 477 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-08-18 | PERRY MICHAEL S | Sale (S) | Common Stock | 11,600 | USD 87.30 | USD 1,012,680 | SEC filing ↗ |
| 2026-08-18 | OLUKOTUN ADEOYE Y | Sale (S) | Common Stock | 2,000 | USD 86.96 | USD 173,920 | SEC filing ↗ |
| 2026-06-15 | Cohen Matthew Gregory | Award / grant (A) | Common Stock | 11,882 | USD 0.00 | USD 0 | SEC filing ↗ |
Show recent Form 4 evidence (30 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-08-18 | PERRY MICHAEL S | Sale (S) | Common Stock | 11,600 | USD 87.30 | USD 1,012,680 | SEC filing ↗ |
| 2026-08-18 | OLUKOTUN ADEOYE Y | Sale (S) | Common Stock | 2,000 | USD 86.96 | USD 173,920 | SEC filing ↗ |
| 2026-06-15 | Cohen Matthew Gregory | Award / grant (A) | Common Stock | 11,882 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-05-12 | Lu Hongbo | Sale (S) | Common Stock | 2,970 | USD 76.88 | USD 228,334 | SEC filing ↗ |
| 2026-04-23 | Hamilton James C | Sale (S) | Common Stock | 10,000 | USD 75.00 | USD 750,000 | SEC filing ↗ |
| 2026-04-22 | Apel Daniel Joseph | Sale (S) | Common Stock | 13,095 | USD 71.35 | USD 934,285 | SEC filing ↗ |
| 2026-03-05 | Hamilton James C | Sale (S) | Common Stock | 10,000 | USD 64.19 | USD 641,900 | SEC filing ↗ |
| 2026-01-06 | O'Brien Patrick | Gift (G) | Common Stock | 980 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-01-06 | O'Brien Patrick | Award / grant (A) | Common Stock | 75,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-01-06 | Hamilton James C | Award / grant (A) | Common Stock | 75,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-01-06 | Apel Daniel Joseph | Award / grant (A) | Common Stock | 75,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-01-05 | O'Brien Patrick | Sale (S) | Common Stock | 49,493 | USD 63.11 | USD 3,123,349 | SEC filing ↗ |
| 2026-01-05 | Hamilton James C | Sale (S) | Common Stock | 40,164 | USD 63.11 | USD 2,534,661 | SEC filing ↗ |
| 2026-01-02 | Anzalone Christopher Richard | Sale (S) | Common Stock | 13,187 | USD 66.10 | USD 871,703 | SEC filing ↗ |
| 2025-12-31 | O'Brien Patrick | Gift (G) | Common Stock | 560 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-29 | Anzalone Christopher Richard | Sale (S) | Common Stock | 51,726 | USD 69.13 | USD 3,575,575 | SEC filing ↗ |
| 2025-12-29 | Anzalone Christopher Richard | Option exercise / conversion (M) | Common Stock | 51,726 | USD 6.15 | USD 318,115 | SEC filing ↗ |
| 2025-12-26 | Ferrari Mauro | Sale (S) | Common Stock | 7,530 | USD 70.00 | USD 527,100 | SEC filing ↗ |
| 2025-12-22 | Anzalone Christopher Richard | Sale (S) | Common Stock | 12,586 | USD 68.44 | USD 861,340 | SEC filing ↗ |
| 2025-12-19 | Waddill William D. | Sale (S) | Common Stock | 8,367 | USD 67.65 | USD 566,038 | SEC filing ↗ |
| 2025-12-19 | Vakiener Victoria | Sale (S) | Common Stock | 10,040 | USD 67.68 | USD 679,491 | SEC filing ↗ |
| 2025-12-19 | OLUKOTUN ADEOYE Y | Sale (S) | Common Stock | 10,000 | USD 67.66 | USD 676,623 | SEC filing ↗ |
| 2025-12-19 | Anzalone Christopher Richard | Sale (S) | Common Stock | 13,445 | USD 67.66 | USD 909,683 | SEC filing ↗ |
| 2025-12-17 | Anzalone Christopher Richard | Sale (S) | Common Stock | 85,000 | USD 64.04 | USD 5,443,462 | SEC filing ↗ |
| 2025-12-16 | Waddill William D. | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-16 | Vakiener Victoria | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-16 | PERRY MICHAEL S | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-16 | OLUKOTUN ADEOYE Y | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-16 | Lu Hongbo | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2025-12-16 | INGRAM DOUGLAS S | Award / grant (A) | Common Stock | 7,819 | USD 0.00 | USD 0 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-18 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | ARWR |
| CIK | 0000879407 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 477 transaction lines from 2020-01-01 to 2026-08-18 19 P purchase lines · 312 S sale lines · 146 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.