← United States · Coverage record
US · SEC FORM 4
Axsome Therapeutics, Inc.
AXSM · Nasdaq · CIK 0001579428 · Healthcare · Biotechnology
INSIDER SIGNAL
0 qualifying P purchase groups
in the current 180-day scoring window
30 Form 4 transaction lines observed in the same window
17 sales · 13 option, withholding, award, gift or other lines
WHY NO ACTIVE SIGNAL?
Score anatomy
No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.
Why is there no score?
- No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
- Sales and other Form 4 activity remain visible as context and do not create a negative score.
Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
Showing the six most active owners; 2 additional owner(s) remain in Form 4 evidence.
Purchase breadth, concentration & cluster buying
These modules activate when qualifying purchases enter the 180-day research window.
SIGNAL HISTORY
Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2025-09-08 · Coleman Mark.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context provides additional background on recent price performance and risk. It does not affect the Insider Signal.
Price performance
- 1M
- -24.8%
- 3M
- -29.4%
- 6M
- -6.9%
- 12M
- +35.5%
Volatility & liquidity
- Volatility
- 44.6%
- Beta
- —
- Avg daily value
- USD 118.6M
Valuation
- Market cap
- USD 8.7B
- P/E
- —
Fundamentals
- Profit margin
- -28.7%
- ROE
- -207.5%
- Industry
- Biotechnology
Market data
Price data up to: 2026-10-12 · Price source: OpenBB/yfinance; volume from price cache (yfinance) · From SEC filings: Market cap, Profit margin, ROE · Fiscal year ended: 2025-12-31 · Market cap is the shares outstanding stated on the filing cover multiplied by the latest close. Share count date: 2026-08-03 · Status: PASS
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 3,306,417
- Previous report
- 3,139,787
- Avg daily volume
- 758,360
- Days to cover
- 4.4
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2025-09-08 | Coleman Mark | Purchase (P) | Common Stock | 1,575 | USD 127.28 | USD 200,466 | SEC filing ↗ |
| 2021-11-19 | JEFFS ROGER | Purchase (P) | Common Stock | 3,950 | USD 37.30 | USD 147,335 | SEC filing ↗ |
| 2021-11-18 | Pizzie Nick | Purchase (P) | Common Stock | 955 | USD 35.26 | USD 33,676 | SEC filing ↗ |
| 2021-11-18 | Coleman Mark | Purchase (P) | Common Stock | 1,430 | USD 35.09 | USD 50,181 | SEC filing ↗ |
| 2021-11-17 | Saad Mark E | Purchase (P) | Common Stock | 3,200 | USD 34.52 | USD 110,475 | SEC filing ↗ |
| 2021-05-12 | Coleman Mark | Purchase (P) | Common Stock | 500 | USD 58.15 | USD 29,075 | SEC filing ↗ |
| 2020-06-29 | Pizzie Nick | Purchase (P) | Common Stock | 777 | USD 76.64 | USD 59,549 | SEC filing ↗ |
| 2020-06-29 | Coleman Mark | Purchase (P) | Common Stock | 650 | USD 78.50 | USD 51,025 | SEC filing ↗ |
Form 4 evidence
64 transaction lines in the latest 365-day window; 157 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-03 | Jacobson Mark L. | Sale (S) | Common Stock | 10,000 | USD 208.65 | USD 2,086,500 | SEC filing ↗ |
| 2026-09-03 | Jacobson Mark L. | Option exercise / conversion (M) | Common Stock | 10,000 | USD 12.95 | USD 129,500 | SEC filing ↗ |
| 2026-08-06 | TABUTEAU HERRIOT | Sale (S) | Common Stock | 4,660 | USD 213.95 | USD 997,007 | SEC filing ↗ |
Show recent Form 4 evidence (30 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-03 | Jacobson Mark L. | Sale (S) | Common Stock | 10,000 | USD 208.65 | USD 2,086,500 | SEC filing ↗ |
| 2026-09-03 | Jacobson Mark L. | Option exercise / conversion (M) | Common Stock | 10,000 | USD 12.95 | USD 129,500 | SEC filing ↗ |
| 2026-08-06 | TABUTEAU HERRIOT | Sale (S) | Common Stock | 4,660 | USD 213.95 | USD 997,007 | SEC filing ↗ |
| 2026-08-06 | TABUTEAU HERRIOT | Option exercise / conversion (M) | Common Stock | 4,660 | USD 4.95 | USD 23,067 | SEC filing ↗ |
| 2026-08-05 | TABUTEAU HERRIOT | Sale (S) | Common Stock | 45,004 | USD 212.01 | USD 9,541,298 | SEC filing ↗ |
| 2026-08-05 | TABUTEAU HERRIOT | Option exercise / conversion (M) | Common Stock | 45,004 | USD 4.95 | USD 222,770 | SEC filing ↗ |
| 2026-07-01 | TABUTEAU HERRIOT | Sale (S) | Common Stock | 49,666 | USD 240.25 | USD 11,932,256 | SEC filing ↗ |
| 2026-07-01 | TABUTEAU HERRIOT | Option exercise / conversion (M) | Common Stock | 49,666 | USD 4.95 | USD 245,847 | SEC filing ↗ |
| 2026-06-11 | JEFFS ROGER | Sale (S) | Common Stock | 286 | USD 249.12 | USD 71,248 | SEC filing ↗ |
| 2026-06-10 | JEFFS ROGER | Sale (S) | Common Stock | 286 | USD 246.18 | USD 70,407 | SEC filing ↗ |
| 2026-06-10 | Mahony Susan | Sale (S) | Common Stock | 300 | USD 246.18 | USD 73,854 | SEC filing ↗ |
| 2026-06-10 | Coleman Mark | Sale (S) | Common Stock | 643 | USD 249.00 | USD 160,107 | SEC filing ↗ |
| 2026-06-09 | Mahony Susan | Sale (S) | Common Stock | 300 | USD 237.21 | USD 71,163 | SEC filing ↗ |
| 2026-06-09 | TABUTEAU HERRIOT | Sale (S) | Common Stock | 49,670 | USD 241.01 | USD 11,970,967 | SEC filing ↗ |
| 2026-06-09 | TABUTEAU HERRIOT | Option exercise / conversion (M) | Common Stock | 49,670 | USD 4.95 | USD 245,866 | SEC filing ↗ |
| 2026-06-09 | Pizzie Nick | Sale (S) | Common Stock | 33,000 | USD 240.09 | USD 7,922,970 | SEC filing ↗ |
| 2026-06-09 | Pizzie Nick | Option exercise / conversion (M) | Common Stock | 33,000 | USD 3.50 | USD 115,500 | SEC filing ↗ |
| 2026-06-08 | Saad Mark E | Option exercise / conversion (M) | Common Stock | 1,429 | USD — | USD — | SEC filing ↗ |
| 2026-06-08 | Mahony Susan | Option exercise / conversion (M) | Common Stock | 1,429 | USD — | USD — | SEC filing ↗ |
| 2026-06-08 | JEFFS ROGER | Option exercise / conversion (M) | Common Stock | 1,429 | USD — | USD — | SEC filing ↗ |
| 2026-06-08 | Coleman Mark | Option exercise / conversion (M) | Common Stock | 1,429 | USD — | USD — | SEC filing ↗ |
| 2026-06-02 | Coleman Mark | Sale (S) | Common Stock | 5,537 | USD 223.39 | USD 1,236,910 | SEC filing ↗ |
| 2026-06-01 | Coleman Mark | Sale (S) | Common Stock | 6,000 | USD 230.30 | USD 1,381,800 | SEC filing ↗ |
| 2026-05-29 | Coleman Mark | Sale (S) | Common Stock | 6,000 | USD 233.46 | USD 1,400,760 | SEC filing ↗ |
| 2026-05-05 | Jacobson Mark L. | Sale (S) | Common Stock | 233 | USD 228.18 | USD 53,166 | SEC filing ↗ |
| 2026-05-05 | Jacobson Mark L. | Option exercise / conversion (M) | Common Stock | 233 | USD 12.95 | USD 3,017 | SEC filing ↗ |
| 2026-05-04 | Jacobson Mark L. | Sale (S) | Common Stock | 4,517 | USD 227.94 | USD 1,029,605 | SEC filing ↗ |
| 2026-05-04 | Jacobson Mark L. | Option exercise / conversion (M) | Common Stock | 4,517 | USD 12.95 | USD 58,495 | SEC filing ↗ |
| 2026-04-22 | Maizel Ari | Sale (S) | Common Stock | 7,500 | USD 182.42 | USD 1,368,150 | SEC filing ↗ |
| 2026-04-22 | Maizel Ari | Option exercise / conversion (M) | Common Stock | 7,500 | USD 70.73 | USD 530,475 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-18 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | AXSM |
| CIK | 0001579428 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 157 transaction lines from 2020-01-10 to 2026-09-03 16 P purchase lines · 73 S sale lines · 68 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.