← United States · Coverage record
US · SEC FORM 4
CRESCENT BIOPHARMA, INC.
CBIO · Nasdaq · CIK 0001253689 · Healthcare · Biotechnology
INSIDER SIGNAL
1 buyers · 1 purchase transaction lines · $12.4M gross purchase
WHY THIS SIGNAL?
Score anatomy
Each bar shows the contribution to the current score; the weights and formula stay unchanged.
What is holding the score back?
- ⚠ Cluster breadth is moderate · 1 insider(s), not 4+
- ⚠ Purchase activity is becoming less recent
- ✓ Role scores high · most senior buyer: Director,TenPercentOwner
Purchase-size comments are relative to the model scale. Average daily volume is a separate market-context diagnostic.
US-v1.2 ranks qualifying equity purchases under the current 180-day rules. The score is a research priority, not a return forecast or probability. Backtests have not shown that a higher US score is followed by better returns.
Purchase breadth & concentration
Roles in the peak window: Director,TenPercentOwner. Concentration uses priced qualifying P lines only and does not change the saved score.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
Showing the six most active owners; 2 additional owner(s) remain in Form 4 evidence.
SIGNAL HISTORY
Latest recorded score
- 61.0
- 60.9
- 60.9
Only scores saved when a full US scoring run completed are shown; gaps are not reconstructed.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 4,777,172
- Previous report
- 3,407,158
- Avg daily volume
- 697,402
- Days to cover
- 6.8
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-07-16 | Fairmount Funds Management LLC; Fairmount Healthcare Fund II L.P.; Harwin Peter Evan; Kiselak Tomas | Purchase (P) | Ordinary Shares | 853,450 | USD 14.50 | USD 12,375,025 | SEC filing ↗ |
| 2025-12-04 | Fairmount Funds Management LLC; Fairmount Healthcare Fund II L.P.; Harwin Peter Evan; Kiselak Tomas | Purchase (P) | Ordinary Shares | 1,360,000 | USD 13.41 | USD 18,237,600 | SEC filing ↗ |
| 2024-06-21 | Rock Edwin | Purchase (P) | Common Stock | 115,000 | USD 0.27 | USD 31,050 | SEC filing ↗ |
| 2024-06-20 | Rock Edwin | Purchase (P) | Common Stock | 190,000 | USD 0.25 | USD 47,500 | SEC filing ↗ |
| 2024-06-18 | Hahn Brian M. | Purchase (P) | Common Stock | 17,500 | USD 0.25 | USD 4,375 | SEC filing ↗ |
| 2023-09-22 | Rock Edwin | Purchase (P) | Common Stock | 30,403 | USD 1.38 | USD 41,956 | SEC filing ↗ |
| 2023-09-21 | Rock Edwin | Purchase (P) | Common Stock | 35,000 | USD 1.38 | USD 48,300 | SEC filing ↗ |
| 2023-05-10 | JUNIUS DANIEL M | Purchase (P) | Common Stock | 30,000 | USD 1.56 | USD 46,800 | SEC filing ↗ |
| 2023-05-08 | Johnson Bruce S | Purchase (P) | Common Stock | 13,500 | USD 1.57 | USD 21,195 | SEC filing ↗ |
| 2023-02-24 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 100,000 | USD 1.70 | USD 170,000 | SEC filing ↗ |
| 2023-02-23 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 200,000 | USD 1.75 | USD 350,000 | SEC filing ↗ |
| 2023-02-22 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 150,000 | USD 1.79 | USD 268,500 | SEC filing ↗ |
| 2023-02-21 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 50,000 | USD 1.85 | USD 92,500 | SEC filing ↗ |
| 2023-02-17 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 200,000 | USD 1.71 | USD 342,000 | SEC filing ↗ |
| 2023-02-16 | Artal Group S.A.; Artal International Management S.A.; Artal International S.C.A.; Invus Public Equities Advisors, LLC; Invus Public Equities, L.P.; Stichting Administratiekantoor Westend; Westend S.A.; Wittouck Amaury | Purchase (P) | Common Stock | 315,266 | USD 1.68 | USD 529,647 | SEC filing ↗ |
Form 4 evidence
34 transaction lines in the latest 365-day window; 122 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-18 | McNeill Jonathan | Sale (S) | Ordinary Shares | 3,839 | USD 16.71 | USD 64,150 | SEC filing ↗ |
| 2026-09-18 | Brumm Joshua T | Sale (S) | Ordinary Shares | 7,837 | USD 16.71 | USD 130,956 | SEC filing ↗ |
| 2026-09-16 | Scalzo Richard William | Sale (S) | Ordinary Shares | 568 | USD 17.90 | USD 10,167 | SEC filing ↗ |
Show recent Form 4 evidence (26 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-18 | McNeill Jonathan | Sale (S) | Ordinary Shares | 3,839 | USD 16.71 | USD 64,150 | SEC filing ↗ |
| 2026-09-18 | Brumm Joshua T | Sale (S) | Ordinary Shares | 7,837 | USD 16.71 | USD 130,956 | SEC filing ↗ |
| 2026-09-16 | Scalzo Richard William | Sale (S) | Ordinary Shares | 568 | USD 17.90 | USD 10,167 | SEC filing ↗ |
| 2026-09-16 | Pinkas Jan | Sale (S) | Ordinary Shares | 658 | USD 17.90 | USD 11,778 | SEC filing ↗ |
| 2026-09-16 | McNeill Jonathan | Sale (S) | Ordinary Shares | 731 | USD 17.90 | USD 13,085 | SEC filing ↗ |
| 2026-09-16 | Lynch Ryan | Sale (S) | Ordinary Shares | 240 | USD 17.90 | USD 4,296 | SEC filing ↗ |
| 2026-09-16 | Im Ellie Eunkyung | Sale (S) | Ordinary Shares | 623 | USD 17.90 | USD 11,152 | SEC filing ↗ |
| 2026-09-16 | Brumm Joshua T | Sale (S) | Ordinary Shares | 1,610 | USD 17.90 | USD 28,819 | SEC filing ↗ |
| 2026-09-16 | Bispham Barbara Harlin | Sale (S) | Ordinary Shares | 620 | USD 17.90 | USD 11,098 | SEC filing ↗ |
| 2026-07-16 | Fairmount Funds Management LLC; Fairmount Healthcare Fund II L.P.; Harwin Peter Evan; Kiselak Tomas | Purchase (P) | Ordinary Shares | 853,450 | USD 14.50 | USD 12,375,025 | SEC filing ↗ |
| 2026-06-22 | Scalzo Richard William | Sale (S) | Ordinary Shares | 1,112 | USD 17.99 | USD 20,005 | SEC filing ↗ |
| 2026-06-22 | Pinkas Jan | Sale (S) | Ordinary Shares | 1,288 | USD 17.99 | USD 23,171 | SEC filing ↗ |
| 2026-06-22 | McNeill Jonathan | Sale (S) | Ordinary Shares | 20,549 | USD 17.99 | USD 369,677 | SEC filing ↗ |
| 2026-06-22 | Lynch Ryan | Sale (S) | Ordinary Shares | 465 | USD 17.99 | USD 8,365 | SEC filing ↗ |
| 2026-06-22 | Im Ellie Eunkyung | Sale (S) | Ordinary Shares | 1,219 | USD 17.99 | USD 21,930 | SEC filing ↗ |
| 2026-06-22 | Brumm Joshua T | Sale (S) | Ordinary Shares | 42,305 | USD 17.99 | USD 761,067 | SEC filing ↗ |
| 2026-06-22 | Bispham Barbara Harlin | Sale (S) | Ordinary Shares | 1,218 | USD 17.99 | USD 21,912 | SEC filing ↗ |
| 2025-12-15 | Scalzo Richard William | Award / grant (A) | Ordinary Shares | 19,422 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Pinkas Jan | Award / grant (A) | Ordinary Shares | 22,507 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | McNeill Jonathan | Award / grant (A) | Ordinary Shares | 25,507 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Lynch Ryan | Award / grant (A) | Ordinary Shares | 12,378 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Im Ellie Eunkyung | Award / grant (A) | Ordinary Shares | 21,298 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Doughty Christopher Grant | Award / grant (A) | Ordinary Shares | 22,714 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Brumm Joshua T | Award / grant (A) | Ordinary Shares | 55,117 | USD — | USD — | SEC filing ↗ |
| 2025-12-15 | Bispham Barbara Harlin | Award / grant (A) | Ordinary Shares | 18,422 | USD — | USD — | SEC filing ↗ |
| 2025-12-04 | Fairmount Funds Management LLC; Fairmount Healthcare Fund II L.P.; Harwin Peter Evan; Kiselak Tomas | Purchase (P) | Ordinary Shares | 1,360,000 | USD 13.41 | USD 18,237,600 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-19 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | CBIO |
| CIK | 0001253689 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 122 transaction lines from 2020-01-06 to 2026-09-18 34 P purchase lines · 42 S sale lines · 46 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-19. Mapping status is an audit field and does not erase SEC filing evidence.