Stock Trading Canary

United States · SEC Form 4 · Snapshot date: 2026-10-18 · Built: 2026-10-18 · 中文

← United States · Coverage record

US · SEC FORM 4

IONIS PHARMACEUTICALS INC

IONS · Nasdaq · CIK 0000874015 · Healthcare · Biotechnology

INSIDER SIGNAL

No active buy signal

2 qualifying P purchase groups
in the current 180-day scoring window

56 Form 4 transaction lines observed in the same window
24 sales · 30 option, withholding, award, gift or other lines

Last qualifying purchase2026-07-31 · Hayden Michael R · $258.0K

WHY NO ACTIVE SIGNAL?

Purchase activityPresent
Recent buying2 qualifying line group(s)
Recent salesHigh
Buy signal statusInactive
Score anatomy

No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.

ClusterNot calculated
Purchase sizeNot calculated
RoleNot calculated
RecencyNot calculated
ConvictionNot calculated

Why is there no score?

  • No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
  • Sales and other Form 4 activity remain visible as context and do not create a negative score.

Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.

Insider activity timeline

Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.

AprMayJunJulAugSepOct
Monia Brett PChief Executive Officer
○▼○▼○▼○▼○▼○
BERTHELSEN SPENCER RDirector
○▼○▼○
KLEIN JOSEPH IIIDirector
○▼○▼
BENNETT C FRANKEVP, Chief Scientific Officer
○▼○
Baroldi JosephEVP, Chief Business Officer
▼○▼
Kordasiewicz Holly B.EVP, Chief Development Officer
○▼▼
● Purchase▼ Sale○ Other

Showing the six most active owners; 8 additional owner(s) remain in Form 4 evidence.

Purchase breadth & concentration

QUALIFYING BUYERS1
PURCHASE CONCENTRATION100%Largest buyer: Hayden Michael R · $1.1M
CLUSTER BUYING · 15D1 insiderPeak activity: 2026-07-30–2026-07-31

Roles in the peak window: Director. Concentration uses priced qualifying P lines only and does not change the saved score.

SIGNAL HISTORY

No recorded active-signal snapshot

Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2026-07-31 · Hayden Michael R.

Recent Form 4 activity

2Purchases
122Sales
115Other Form 4 lines
84SEC filings · 365 days
BUYING2 qualifying P line(s) · 180 days
SELLING24 sale line(s) · context only
OTHER30 exercise / withholding / award / gift / other lines
10b5-1 / PLANNEDNot assessed

P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.

Market context

Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.

Short interest

Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.

Shares short
22,508,744
Previous report
20,890,252
Avg daily volume
4,881,042
Days to cover
4.6

FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.

Historical equity purchases

Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.

Transaction dateReporting ownerTypeSecuritySharesAvg. priceApprox. valueSource
2026-07-31Hayden Michael RPurchase (P)Common Stock5,000USD 51.60USD 258,000SEC filing ↗
2026-07-30Hayden Michael RPurchase (P)Common Stock15,000USD 53.38USD 800,700SEC filing ↗
2025-05-01Hayden Michael RPurchase (P)Common Stock15,000USD 31.86USD 477,900SEC filing ↗
2024-12-23Hayden Michael RPurchase (P)Common Stock5,000USD 36.22USD 181,075SEC filing ↗

Form 4 evidence

239 transaction lines in the latest 365-day window; 923 in local history.

DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-08-31O'NEIL PATRICK R.J (J)Common Stock63USD 51.31USD 3,233SEC filing ↗
2026-08-31Monia Brett PJ (J)Common Stock98USD 51.31USD 5,028SEC filing ↗
2026-08-31Birchler BrianJ (J)Common Stock58USD 51.31USD 2,976SEC filing ↗
Show recent Form 4 evidence (30 grouped rows)
DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-08-31O'NEIL PATRICK R.J (J)Common Stock63USD 51.31USD 3,233SEC filing ↗
2026-08-31Monia Brett PJ (J)Common Stock98USD 51.31USD 5,028SEC filing ↗
2026-08-31Birchler BrianJ (J)Common Stock58USD 51.31USD 2,976SEC filing ↗
2026-08-31BENNETT C FRANKJ (J)Common Stock110USD 51.31USD 5,644SEC filing ↗
2026-07-31Hayden Michael RPurchase (P)Common Stock5,000USD 51.60USD 258,000SEC filing ↗
2026-07-30Hayden Michael RPurchase (P)Common Stock15,000USD 53.38USD 800,700SEC filing ↗
2026-07-15HERMAN JOAN EOption exercise / conversion (M)Common Stock5,220USD 0.00USD 0SEC filing ↗
2026-07-15BERTHELSEN SPENCER ROption exercise / conversion (M)Common Stock5,220USD 0.00USD 0SEC filing ↗
2026-07-07Kordasiewicz Holly B.Sale (S)Common Stock362USD 84.30USD 30,517SEC filing ↗
2026-07-07Diaz Allene M.Sale (S)Common Stock10,111USD 85.42USD 863,682SEC filing ↗
2026-07-07Diaz Allene M.Option exercise / conversion (M)Common Stock10,111USD 47.11USD 476,329SEC filing ↗
2026-07-07BENNETT C FRANKSale (S)Common Stock20,536USD 84.95USD 1,744,599SEC filing ↗
2026-07-07BENNETT C FRANKJ (J)Common Stock15,000USD 0.00USD 0SEC filing ↗
2026-07-01KLEIN JOSEPH IIISale (S)Common Stock11,518USD 79.04USD 910,423SEC filing ↗
2026-07-01KLEIN JOSEPH IIIOption exercise / conversion (M)Common Stock11,518USD 39.94USD 460,029SEC filing ↗
2026-06-26Schneider EugeneSale (S)Common Stock26,000USD 81.05USD 2,107,300SEC filing ↗
2026-06-26Schneider EugeneOption exercise / conversion (M)Common Stock26,000USD 60.89USD 1,583,140SEC filing ↗
2026-06-26O'NEIL PATRICK R.Sale (S)Common Stock3,069USD 80.00USD 245,520SEC filing ↗
2026-06-26Baroldi JosephSale (S)Common Stock5,635USD 80.16USD 451,702SEC filing ↗
2026-06-26Baroldi JosephOption exercise / conversion (M)Common Stock5,635USD 49.19USD 277,181SEC filing ↗
2026-06-26Monia Brett PSale (S)Common Stock50,000USD 80.59USD 4,029,500SEC filing ↗
2026-06-26Monia Brett POption exercise / conversion (M)Common Stock50,000USD 56.78USD 2,839,000SEC filing ↗
2026-06-25Swayze EricSale (S)Common Stock10,602USD 79.18USD 839,466SEC filing ↗
2026-06-25Monia Brett PSale (S)Common Stock21,072USD 78.49USD 1,653,941SEC filing ↗
2026-06-25Monia Brett POption exercise / conversion (M)Common Stock21,072USD 32.60USD 686,947SEC filing ↗
2026-06-24Monia Brett PSale (S)Common Stock14,565USD 78.41USD 1,142,042SEC filing ↗
2026-06-24Monia Brett POption exercise / conversion (M)Common Stock14,565USD 32.60USD 474,819SEC filing ↗
2026-06-15BERTHELSEN SPENCER RSale (S)Common Stock8,000USD 73.49USD 587,920SEC filing ↗
2026-06-15BERTHELSEN SPENCER ROption exercise / conversion (M)Common Stock8,000USD 24.42USD 195,360SEC filing ↗
2026-06-12Kordasiewicz Holly B.Sale (S)Common Stock60,846USD 73.40USD 4,466,282SEC filing ↗

Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.

Snapshot & identity

Snapshot date2026-10-18
Ranking versionUS-v1.2
Data qualityPASS ELIGIBLE · —
TickerIONS
CIK0000874015
SectorHealthcare
IndustryBiotechnology Yahoo Finance
SEC SIC2834 Pharmaceutical Preparations
ExchangeNasdaq

Data coverage

Local Form 4 history923 transaction lines from 2020-01-02 to 2026-08-31
5 P purchase lines · 387 S sale lines · 531 other lines
SEC company submissionsOpen SEC filings ↗

Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.