← United States · Coverage record
US · SEC FORM 4
Lyra Therapeutics, Inc.
LYRA · — · CIK 0001327273 · Healthcare · Biotechnology
INSIDER SIGNAL
0 qualifying P purchase groups
in the current 180-day scoring window
1 Form 4 transaction lines observed in the same window
0 sales · 1 option, withholding, award, gift or other lines
WHY NO ACTIVE SIGNAL?
Score anatomy
No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.
Why is there no score?
- No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
- Sales and other Form 4 activity remain visible as context and do not create a negative score.
Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.
Purchase breadth, concentration & cluster buying
These modules activate when qualifying purchases enter the 180-day research window.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
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SIGNAL HISTORY
Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2023-11-10 · Waksal Harlan.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 4,882
- Previous report
- 4,895
- Avg daily volume
- 1,191
- Days to cover
- 4.1
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2023-11-10 | Waksal Harlan | Purchase (P) | Common Stock | 25,000 | USD 2.96 | USD 74,000 | SEC filing ↗ |
| 2023-05-31 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Purchase (P) | Common Stock | 3,610,832 | USD 2.49 | USD 8,990,972 | SEC filing ↗ |
| 2023-05-31 | DAMORE RICHARD A; NBVM GP, LLC; NORTH BRIDGE VENTURE PARTNERS V A LP; NORTH BRIDGE VENTURE PARTNERS V-B LP; North Bridge Venture Management V, L.P.; North Bridge Venture Management VI, L.P.; North Bridge Venture Partners VI L P | Purchase (P) | Common Stock | 1,805,416 | USD 2.43 | USD 4,387,161 | SEC filing ↗ |
| 2023-05-31 | ANDERSON EDWARD T | Purchase (P) | Common Stock | 1,805,416 | USD 2.43 | USD 4,387,161 | SEC filing ↗ |
| 2022-06-10 | MERRIFIELD C ANN | Purchase (P) | Common Stock | 4,000 | USD 5.05 | USD 20,200 | SEC filing ↗ |
| 2022-05-16 | MERRIFIELD C ANN | Purchase (P) | Common Stock | 328 | USD 5.00 | USD 1,640 | SEC filing ↗ |
| 2022-05-13 | MERRIFIELD C ANN | Purchase (P) | Common Stock | 3,500 | USD 4.81 | USD 16,835 | SEC filing ↗ |
| 2022-04-12 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Purchase (P) | Common Stock | 5,924,170 | USD 4.22 | USD 24,999,997 | SEC filing ↗ |
| 2022-04-12 | DAMORE RICHARD A; NBVM GP, LLC; NORTH BRIDGE VENTURE PARTNERS V A LP; NORTH BRIDGE VENTURE PARTNERS V-B LP; North Bridge Venture Management V, L.P.; North Bridge Venture Management VI, L.P.; North Bridge Venture Partners VI L P | Purchase (P) | Common Stock | 2,369,667 | USD 4.22 | USD 9,999,995 | SEC filing ↗ |
| 2022-04-12 | ANDERSON EDWARD T | Purchase (P) | Common Stock | 2,488,150 | USD 4.22 | USD 10,499,993 | SEC filing ↗ |
| 2022-04-12 | Waksal Harlan | Purchase (P) | Common Stock | 236,966 | USD 4.22 | USD 999,997 | SEC filing ↗ |
| 2021-06-17 | MERRIFIELD C ANN | Purchase (P) | Common Stock | 3,500 | USD 8.97 | USD 31,395 | SEC filing ↗ |
| 2020-12-16 | snyderman nancy lynn MD | Purchase (P) | Common Stock | 1,025 | USD 9.72 | USD 9,963 | SEC filing ↗ |
| 2020-05-05 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Purchase (P) | Common Stock | 625,000 | USD 16.00 | USD 10,000,000 | SEC filing ↗ |
| 2020-05-05 | Levy Guy; Soleus Capital Group, LLC; Soleus Capital Master Fund, L.P.; Soleus Capital, LLC; Soleus PE GP I, LLC; Soleus Private Equity Fund I, L.P.; Soleus Private Equity GP I, LLC | Purchase (P) | Common Stock | 155,000 | USD 16.00 | USD 2,480,000 | SEC filing ↗ |
Form 4 evidence
17 transaction lines in the latest 365-day window; 107 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-05-14 | Smith W Bradford | D (D) | Common Stock | 640 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-01 | Palasis Maria | D (D) | Common Stock | 2,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-01 | Cavalier Jason | D (D) | Common Stock | 667 | USD 0.00 | USD 0 | SEC filing ↗ |
Show recent Form 4 evidence (11 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-05-14 | Smith W Bradford | D (D) | Common Stock | 640 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-01 | Palasis Maria | D (D) | Common Stock | 2,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-04-01 | Cavalier Jason | D (D) | Common Stock | 667 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-01-06 | Palasis Maria | Sale (S) | Common Stock | 1,702 | USD 3.36 | USD 5,719 | SEC filing ↗ |
| 2026-01-06 | Cavalier Jason | Sale (S) | Common Stock | 769 | USD 3.36 | USD 2,584 | SEC filing ↗ |
| 2025-11-13 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 31,810 | USD 3.90 | USD 124,059 | SEC filing ↗ |
| 2025-11-12 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 8,745 | USD 4.06 | USD 35,505 | SEC filing ↗ |
| 2025-11-11 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 5,320 | USD 4.31 | USD 22,929 | SEC filing ↗ |
| 2025-11-10 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 18,502 | USD 4.54 | USD 83,999 | SEC filing ↗ |
| 2025-11-07 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 19,739 | USD 4.75 | USD 93,760 | SEC filing ↗ |
| 2025-11-06 | EDELMAN JOSEPH; PERCEPTIVE ADVISORS LLC; PERCEPTIVE LIFE SCIENCES MASTER FUND LTD; Perceptive LS (A), LLC | Sale (S) | Common Stock | 32,149 | USD 5.18 | USD 166,532 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-19 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | LYRA |
| CIK | 0001327273 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 3841 Surgical & Medical Instruments & Apparatus |
| Exchange | — |
Data coverage
| Local Form 4 history | 107 transaction lines from 2020-05-01 to 2026-05-14 34 P purchase lines · 27 S sale lines · 46 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-19. Mapping status is an audit field and does not erase SEC filing evidence.