Stock Trading Canary

United States · SEC Form 4 · Snapshot date: 2026-10-19 · Built: 2026-10-19 · 中文

← United States · Coverage record

US · SEC FORM 4

MADRIGAL PHARMACEUTICALS, INC.

MDGL · Nasdaq · CIK 0001157601 · Healthcare · Biotechnology

INSIDER SIGNAL

No active buy signal

0 qualifying P purchase groups
in the current 180-day scoring window

57 Form 4 transaction lines observed in the same window
49 sales · 8 option, withholding, award, gift or other lines

Last qualifying purchase2025-08-20 · 667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP · $23.1M

WHY NO ACTIVE SIGNAL?

Purchase activityNone
Recent buyingNone
Recent salesHigh
Buy signal statusInactive
Score anatomy

No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.

ClusterNot calculated
Purchase sizeNot calculated
RoleNot calculated
RecencyNot calculated
ConvictionNot calculated

Why is there no score?

  • No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
  • Sales and other Form 4 activity remain visible as context and do not create a negative score.

Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.

Purchase breadth, concentration & cluster buying

These modules activate when qualifying purchases enter the 180-day research window.

Insider activity timeline

Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.

AprMayJunJulAugSepOct
Sibold William JohnPresident and CEO
○▼▼▼
Levy Richard SDirector
▼○
Soergel DavidChief Medical Officer
▼▼
Taub RebeccaDirector
○
FOUSE JACQUALYN ADirector
○
Daly James MDirector
○
● Purchase▼ Sale○ Other

Showing the six most active owners; 4 additional owner(s) remain in Form 4 evidence.

SIGNAL HISTORY

No recorded active-signal snapshot

Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2025-08-20 · 667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP.

Recent Form 4 activity

0Purchases
202Sales
30Other Form 4 lines
39SEC filings · 365 days
BUYING0 qualifying P line(s) · 180 days
SELLING49 sale line(s) · context only
OTHER8 exercise / withholding / award / gift / other lines
10b5-1 / PLANNEDNot assessed

P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.

Market context

Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.

Short interest

Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.

Shares short
2,396,369
Previous report
2,254,423
Avg daily volume
245,001
Days to cover
9.8

FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.

Historical equity purchases

Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.

Transaction dateReporting ownerTypeSecuritySharesAvg. priceApprox. valueSource
2025-08-20667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock59,901USD 385.16USD 23,071,405SEC filing ↗
2025-08-18667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock37,164USD 373.21USD 13,869,821SEC filing ↗
2025-08-18667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock68,618USD 364.04USD 24,979,848SEC filing ↗
2023-12-14667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock20,633USD 228.32USD 4,710,910SEC filing ↗
2023-12-13667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock81,159USD 219.39USD 17,805,862SEC filing ↗
2023-12-12667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock34,578USD 218.31USD 7,548,577SEC filing ↗
2023-11-21667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock64,350USD 188.47USD 12,128,192SEC filing ↗
2023-11-20667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock20,709USD 185.75USD 3,846,622SEC filing ↗
2023-11-17667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock46,370USD 174.70USD 8,100,636SEC filing ↗
2023-11-15667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock15,199USD 161.97USD 2,461,782SEC filing ↗
2023-11-14667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock34,188USD 156.42USD 5,347,687SEC filing ↗
2023-11-14667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock37,660USD 154.00USD 5,799,623SEC filing ↗
2023-11-13667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPPurchase (P)Common Stock69,839USD 143.21USD 10,001,444SEC filing ↗

Form 4 evidence

232 transaction lines in the latest 365-day window; 889 in local history.

DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-09-11Sibold William JohnSale (S)Common Stock5,221USD 542.38USD 2,831,792SEC filing ↗
2026-09-09Sibold William JohnSale (S)Common Stock6,362USD 535.59USD 3,407,392SEC filing ↗
2026-08-17Kelley Shannon TSale (S)Common Stock664USD 514.97USD 341,940SEC filing ↗
Show recent Form 4 evidence (30 grouped rows)
DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-09-11Sibold William JohnSale (S)Common Stock5,221USD 542.38USD 2,831,792SEC filing ↗
2026-09-09Sibold William JohnSale (S)Common Stock6,362USD 535.59USD 3,407,392SEC filing ↗
2026-08-17Kelley Shannon TSale (S)Common Stock664USD 514.97USD 341,940SEC filing ↗
2026-08-15REED JOHN CAward / grant (A)Common Stock647USD 0.00USD 0SEC filing ↗
2026-07-20Sibold William JohnSale (S)Common Stock2,500USD 547.30USD 1,368,253SEC filing ↗
2026-07-17Sibold William JohnOption exercise / conversion (M)Common Stock50,000USD —USD —SEC filing ↗
2026-06-17Taub RebeccaAward / grant (A)Common Stock454USD 0.00USD 0SEC filing ↗
2026-06-17Levy Richard SAward / grant (A)Common Stock454USD 0.00USD 0SEC filing ↗
2026-06-17FOUSE JACQUALYN AAward / grant (A)Common Stock454USD 0.00USD 0SEC filing ↗
2026-06-17Daly James MAward / grant (A)Common Stock454USD 0.00USD 0SEC filing ↗
2026-06-17Brennan Daniel J.Award / grant (A)Common Stock404USD 0.00USD 0SEC filing ↗
2026-06-17667, L.P.; BAKER BROS. ADVISORS LP; BAKER FELIX; BAKER JULIAN; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LPAward / grant (A)Common Stock908USD 0.00USD 0SEC filing ↗
2026-06-01Soergel DavidSale (S)Common Stock1,042USD 495.74USD 516,561SEC filing ↗
2026-05-22Levy Richard SSale (S)Common Stock5,682USD 515.44USD 2,928,718SEC filing ↗
2026-05-18Soergel DavidSale (S)Common Stock844USD 515.90USD 435,420SEC filing ↗
2026-03-06Taub RebeccaSale (S)Common Stock491USD 431.94USD 212,083SEC filing ↗
2026-03-06Sibold William JohnSale (S)Common Stock1,663USD 431.94USD 718,316SEC filing ↗
2026-03-06Kelley Shannon TSale (S)Common Stock360USD 431.94USD 155,498SEC filing ↗
2026-03-06Huntsman CaroleSale (S)Common Stock419USD 431.94USD 180,983SEC filing ↗
2026-03-06Dier MardiSale (S)Common Stock1,982USD 430.87USD 853,993SEC filing ↗
2026-03-04Soergel DavidAward / grant (A)Common Stock4,374USD 0.00USD 0SEC filing ↗
2026-03-04Sibold William JohnAward / grant (A)Common Stock14,995USD 0.00USD 0SEC filing ↗
2026-03-04Kelley Shannon TAward / grant (A)Common Stock4,017USD 0.00USD 0SEC filing ↗
2026-03-04Huntsman CaroleAward / grant (A)Common Stock3,989USD 0.00USD 0SEC filing ↗
2026-03-04Dier MardiAward / grant (A)Common Stock5,215USD 0.00USD 0SEC filing ↗
2026-03-02Dier MardiSale (S)Common Stock1,183USD 427.21USD 505,389SEC filing ↗
2026-02-23Levy Richard SOption exercise / conversion (M)Common Stock2,500USD 7.36USD 18,400SEC filing ↗
2026-01-26Taub RebeccaSale (S)Common Stock647USD 492.42USD 318,596SEC filing ↗
2026-01-26Sibold William JohnSale (S)Common Stock1,577USD 492.42USD 776,546SEC filing ↗
2026-01-26Levy Richard SOption exercise / conversion (M)Common Stock4,000USD 16.46USD 65,840SEC filing ↗

Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.

Snapshot & identity

Snapshot date2026-10-19
Ranking versionUS-v1.2
Data qualityPASS ELIGIBLE · —
TickerMDGL
CIK0001157601
SectorHealthcare
IndustryBiotechnology Yahoo Finance
SEC SIC2834 Pharmaceutical Preparations
ExchangeNasdaq

Data coverage

Local Form 4 history889 transaction lines from 2020-05-27 to 2026-09-11
192 P purchase lines · 531 S sale lines · 166 other lines
SEC company submissionsOpen SEC filings ↗

Local ledger as of 2026-10-19. Mapping status is an audit field and does not erase SEC filing evidence.