Stock Trading Canary

United States · SEC Form 4 · Snapshot date: 2026-10-19 · Built: 2026-10-19 · 中文

← United States · Coverage record

US · SEC FORM 4

Septerna, Inc.

SEPN · Nasdaq · CIK 0001984086 · Healthcare · Biotechnology

INSIDER SIGNAL

No active buy signal

0 qualifying P purchase groups
in the current 180-day scoring window

33 Form 4 transaction lines observed in the same window
18 sales · 15 option, withholding, award, gift or other lines

Last qualifying purchase2025-03-07 · Ezekowitz Alan · $92.3K

WHY NO ACTIVE SIGNAL?

Purchase activityNone
Recent buyingNone
Recent salesHigh
Buy signal statusInactive
Score anatomy

No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.

ClusterNot calculated
Purchase sizeNot calculated
RoleNot calculated
RecencyNot calculated
ConvictionNot calculated

Why is there no score?

  • No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
  • Sales and other Form 4 activity remain visible as context and do not create a negative score.

Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.

Purchase breadth, concentration & cluster buying

These modules activate when qualifying purchases enter the 180-day research window.

Insider activity timeline

Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.

AprMayJunJulAugSepOct
Shaikhly SamiraChief People Officer
○▼○▼○▼○▼
Long Daniel D.SVP, Drug Discovery
○▼○▼○▼○▼
Bhatt ElizabethPresident and COO
○▼○▼
TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.TenPercentOwner
▼
Kolchinsky Peter; RA CAPITAL MANAGEMENT, L.P.; RA Capital Healthcare Fund LP; RA Capital Nexus Fund III, L.P.; Shah Rajeev M.Director; Director,TenPercentOwner
▼
● Purchase▼ Sale○ Other

—

SIGNAL HISTORY

No recorded active-signal snapshot

Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2025-03-07 · Ezekowitz Alan.

Recent Form 4 activity

0Purchases
26Sales
20Other Form 4 lines
16SEC filings · 365 days
BUYING0 qualifying P line(s) · 180 days
SELLING18 sale line(s) · context only
OTHER15 exercise / withholding / award / gift / other lines
10b5-1 / PLANNEDNot assessed

P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.

Market context

Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.

Short interest

Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.

Shares short
3,096,190
Previous report
2,894,002
Avg daily volume
351,889
Days to cover
8.8

FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.

Historical equity purchases

Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.

Transaction dateReporting ownerTypeSecuritySharesAvg. priceApprox. valueSource
2025-03-07Ezekowitz AlanPurchase (P)Common Stock13,319USD 6.93USD 92,301SEC filing ↗
2025-03-06Ezekowitz AlanPurchase (P)Common Stock41,355USD 6.00USD 248,130SEC filing ↗
2025-03-05Ezekowitz AlanPurchase (P)Common Stock37,835USD 5.82USD 220,200SEC filing ↗
2025-03-04Ezekowitz AlanPurchase (P)Common Stock7,491USD 6.35USD 47,568SEC filing ↗
2025-02-27Labrucherie Gil MPurchase (P)Common Stock3,718USD 5.85USD 21,750SEC filing ↗
2025-02-27Finer JeffreyPurchase (P)Common Stock3,000USD 5.80USD 17,400SEC filing ↗
2025-02-26Finer JeffreyPurchase (P)Common Stock4,000USD 5.70USD 22,800SEC filing ↗
2025-02-25Labrucherie Gil MPurchase (P)Common Stock6,282USD 5.59USD 35,116SEC filing ↗
2025-02-25Finer JeffreyPurchase (P)Common Stock10,000USD 5.68USD 56,800SEC filing ↗
2025-02-24TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.Purchase (P)Common Stock18,861USD 6.00USD 113,166SEC filing ↗
2025-02-21TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.Purchase (P)Common Stock427,668USD 5.94USD 2,540,348SEC filing ↗
2025-02-21Labrucherie Gil MPurchase (P)Common Stock5,000USD 5.85USD 29,250SEC filing ↗
2025-02-20TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.Purchase (P)Common Stock612,674USD 5.92USD 3,627,030SEC filing ↗
2025-02-20Labrucherie Gil MPurchase (P)Common Stock14,500USD 5.88USD 85,260SEC filing ↗
2025-02-19Labrucherie Gil MPurchase (P)Common Stock10,500USD 5.51USD 57,855SEC filing ↗

Form 4 evidence

46 transaction lines in the latest 365-day window; 74 in local history.

DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-09-01Long Daniel D.Sale (S)Common Stock3,333USD 37.83USD 126,087SEC filing ↗
2026-09-01Long Daniel D.Option exercise / conversion (M)Common Stock3,333USD 2.76USD 9,199SEC filing ↗
2026-08-12TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.Sale (S)Common Stock147,200USD 50.27USD 7,399,858SEC filing ↗
Show recent Form 4 evidence (29 grouped rows)
DateOwnerTypeSecuritySharesAvg. priceApprox. valueSource
2026-09-01Long Daniel D.Sale (S)Common Stock3,333USD 37.83USD 126,087SEC filing ↗
2026-09-01Long Daniel D.Option exercise / conversion (M)Common Stock3,333USD 2.76USD 9,199SEC filing ↗
2026-08-12TRV GP V, LLC; TRV GP VI, LLC; Third Rock Ventures GP V, LP; Third Rock Ventures GP VI, L.P.; Third Rock Ventures V, L.P.; Third Rock Ventures VI, L.P.Sale (S)Common Stock147,200USD 50.27USD 7,399,858SEC filing ↗
2026-08-12Kolchinsky Peter; RA CAPITAL MANAGEMENT, L.P.; RA Capital Healthcare Fund LP; RA Capital Nexus Fund III, L.P.; Shah Rajeev M.Sale (S)Common Stock746,500USD 42.50USD 31,726,250SEC filing ↗
2026-08-11Bhatt ElizabethSale (S)Common Stock25,000USD 44.00USD 1,100,000SEC filing ↗
2026-08-11Bhatt ElizabethOption exercise / conversion (M)Common Stock25,000USD 5.79USD 144,658SEC filing ↗
2026-08-03Long Daniel D.Sale (S)Common Stock3,334USD 34.47USD 114,923SEC filing ↗
2026-08-03Long Daniel D.Option exercise / conversion (M)Common Stock3,334USD 2.76USD 9,202SEC filing ↗
2026-07-15Bhatt ElizabethSale (S)Common Stock4,000USD 33.99USD 135,960SEC filing ↗
2026-07-15Bhatt ElizabethOption exercise / conversion (M)Common Stock4,000USD 6.81USD 27,240SEC filing ↗
2026-07-01Long Daniel D.Sale (S)Common Stock3,333USD 34.36USD 114,531SEC filing ↗
2026-07-01Long Daniel D.Option exercise / conversion (M)Common Stock3,333USD 2.76USD 9,199SEC filing ↗
2026-06-29Shaikhly SamiraSale (S)Common Stock2,178USD 35.18USD 76,622SEC filing ↗
2026-06-29Shaikhly SamiraOption exercise / conversion (M)Common Stock2,178USD 6.81USD 14,832SEC filing ↗
2026-06-22Long Daniel D.Sale (S)Common Stock15,000USD 35.51USD 532,590SEC filing ↗
2026-06-22Long Daniel D.Option exercise / conversion (M)Common Stock15,000USD 5.42USD 81,371SEC filing ↗
2026-06-12Shaikhly SamiraSale (S)Common Stock6,250USD 35.08USD 219,250SEC filing ↗
2026-06-12Shaikhly SamiraOption exercise / conversion (M)Common Stock6,250USD 11.70USD 73,125SEC filing ↗
2026-06-01Shaikhly SamiraSale (S)Common Stock5,935USD 28.92USD 171,665SEC filing ↗
2026-06-01Shaikhly SamiraOption exercise / conversion (M)Common Stock5,935USD 1.87USD 11,111SEC filing ↗
2026-05-26Shaikhly SamiraSale (S)Common Stock11,798USD 30.06USD 354,648SEC filing ↗
2026-05-26Shaikhly SamiraOption exercise / conversion (M)Common Stock11,798USD 6.81USD 80,344SEC filing ↗
2026-04-15Bhatt ElizabethSale (S)Common Stock4,000USD 24.34USD 97,354SEC filing ↗
2026-04-15Bhatt ElizabethOption exercise / conversion (M)Common Stock4,000USD 6.81USD 27,240SEC filing ↗
2026-03-02Shaikhly SamiraSale (S)Common Stock70,453USD 28.10USD 1,979,971SEC filing ↗
2026-03-02Shaikhly SamiraOption exercise / conversion (M)Common Stock70,453USD 1.84USD 129,456SEC filing ↗
2026-02-18Bhatt ElizabethSale (S)Common Stock4,000USD 28.96USD 115,856SEC filing ↗
2026-02-18Bhatt ElizabethOption exercise / conversion (M)Common Stock4,000USD 6.81USD 27,240SEC filing ↗
2025-11-10Long Daniel D.Sale (S)Common Stock3,501USD 18.06USD 63,228SEC filing ↗

Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.

Snapshot & identity

Snapshot date2026-10-19
Ranking versionUS-v1.2
Data qualityPASS ELIGIBLE · —
TickerSEPN
CIK0001984086
SectorHealthcare
IndustryBiotechnology Yahoo Finance
SEC SIC2834 Pharmaceutical Preparations
ExchangeNasdaq

Data coverage

Local Form 4 history74 transaction lines from 2024-10-28 to 2026-09-01
19 P purchase lines · 26 S sale lines · 29 other lines
SEC company submissionsOpen SEC filings ↗

Local ledger as of 2026-10-19. Mapping status is an audit field and does not erase SEC filing evidence.