← United States · Coverage record
US · SEC FORM 4
Sionna Therapeutics, Inc.
SION · Nasdaq · CIK 0002036042 · Healthcare · Biotechnology
INSIDER SIGNAL
0 qualifying P purchase groups
in the current 180-day scoring window
22 Form 4 transaction lines observed in the same window
15 sales · 7 option, withholding, award, gift or other lines
WHY NO ACTIVE SIGNAL?
Score anatomy
No score is calculated because there is no qualifying purchase in the active window. Unavailable inputs are not treated as zero or as a bearish signal.
Why is there no score?
- No qualifying open-market purchase supplies cluster, size, role, recency or conviction inputs.
- Sales and other Form 4 activity remain visible as context and do not create a negative score.
Sales and other Form 4 activity are shown separately and do not create a negative buy signal. Absence of buying is not scored as bearish.
Insider activity timeline
Owner lanes show the latest 180 days. Symbol shape identifies the transaction type; sales remain context only.
Showing the six most active owners; 1 additional owner(s) remain in Form 4 evidence.
Purchase breadth, concentration & cluster buying
These modules activate when qualifying purchases enter the 180-day research window.
SIGNAL HISTORY
Scores are archived only when the company qualifies for a published US buy-signal snapshot. Last qualifying purchase: 2025-06-27 · COULTER JAMES G; TPG GP A, LLC; WINKELRIED JON.
Recent Form 4 activity
P is an open-market or private purchase. S is a sale. M, F, A and G usually describe exercises, tax withholding, awards and gifts. These categories remain visually separate.
Market context
Market context has not been captured for this ticker yet. The daily market-context job processes the US universe in rotating batches.
Short interest
Short interest is external context reported to FINRA by broker-dealers. It does not affect the Insider Signal.
- Shares short
- 3,797,732
- Previous report
- 3,966,138
- Avg daily volume
- 1,647,766
- Days to cover
- 2.3
FINRA settlement date: 2026-09-30 · Captured 2026-10-12 · FINRA equity short interest ↗. A share count, published about a week after each of two settlement dates a month; not a percentage of shares outstanding.
Historical equity purchases
Qualifying code P transactions in the local Form 4 history, including purchases outside the current signal window.
| Transaction date | Reporting owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2025-06-27 | COULTER JAMES G; TPG GP A, LLC; WINKELRIED JON | Purchase (P) | Common Stock | 60,000 | USD 15.84 | USD 950,400 | SEC filing ↗ |
| 2025-02-10 | COULTER JAMES G; TPG GP A, LLC; WINKELRIED JON | Purchase (P) | Common Stock | 1,125,000 | USD 18.00 | USD 20,250,000 | SEC filing ↗ |
| 2025-02-10 | Thompson Peter A. | Purchase (P) | Common Stock | 550,000 | USD 18.00 | USD 9,900,000 | SEC filing ↗ |
| 2025-02-10 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Purchase (P) | Common Stock | 550,000 | USD 18.00 | USD 9,900,000 | SEC filing ↗ |
| 2025-02-10 | Kolchinsky Peter; RA CAPITAL MANAGEMENT, L.P.; RA Capital Healthcare Fund LP; RA Capital Nexus Fund III, L.P.; RA Capital Nexus Fund, L.P.; Shah Rajeev M. | Purchase (P) | Common Stock | 1,125,000 | USD 18.00 | USD 20,250,000 | SEC filing ↗ |
| 2025-02-10 | Booth Bruce | Purchase (P) | Common Stock | 60,000 | USD 18.00 | USD 1,080,000 | SEC filing ↗ |
| 2025-02-10 | Atlas Venture Associates Opportunity II, LLC; Atlas Venture Associates Opportunity II, LP; Atlas Venture Associates XI, L.P.; Atlas Venture Associates XI, LLC; Atlas Venture Fund XI, L.P.; Atlas Venture Opportunity Fund II, L.P. | Purchase (P) | Common Stock | 60,000 | USD 18.00 | USD 1,080,000 | SEC filing ↗ |
Form 4 evidence
121 transaction lines in the latest 365-day window; 201 in local history.
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-17 | Kolchinsky Peter; RA CAPITAL MANAGEMENT, L.P.; RA Capital Healthcare Fund LP; RA Capital Nexus Fund III, L.P.; RA Capital Nexus Fund, L.P.; Shah Rajeev M. | Sale (S) | Common Stock | 3,448,811 | USD 6.33 | USD 21,835,018 | SEC filing ↗ |
| 2026-09-17 | Ridloff Elena | Award / grant (A) | Common Stock | 94,537 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-09-17 | McKee Charlotte | Award / grant (A) | Common Stock | 50,000 | USD 0.00 | USD 0 | SEC filing ↗ |
Show recent Form 4 evidence (30 grouped rows)
| Date | Owner | Type | Security | Shares | Avg. price | Approx. value | Source |
|---|---|---|---|---|---|---|---|
| 2026-09-17 | Kolchinsky Peter; RA CAPITAL MANAGEMENT, L.P.; RA Capital Healthcare Fund LP; RA Capital Nexus Fund III, L.P.; RA Capital Nexus Fund, L.P.; Shah Rajeev M. | Sale (S) | Common Stock | 3,448,811 | USD 6.33 | USD 21,835,018 | SEC filing ↗ |
| 2026-09-17 | Ridloff Elena | Award / grant (A) | Common Stock | 94,537 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-09-17 | McKee Charlotte | Award / grant (A) | Common Stock | 50,000 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-09-17 | Fitzpatrick Jennifer | Award / grant (A) | Common Stock | 56,265 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-09-17 | Cloonan Michael | Award / grant (A) | Common Stock | 109,025 | USD 0.00 | USD 0 | SEC filing ↗ |
| 2026-07-07 | Thompson Peter A. | Sale (S) | Common Stock | 85,918 | USD 44.86 | USD 3,854,281 | SEC filing ↗ |
| 2026-07-07 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 85,918 | USD 44.86 | USD 3,854,281 | SEC filing ↗ |
| 2026-07-06 | Fitzpatrick Jennifer | Sale (S) | Common Stock | 10,250 | USD 43.60 | USD 446,900 | SEC filing ↗ |
| 2026-07-06 | Fitzpatrick Jennifer | Option exercise / conversion (M) | Common Stock | 10,250 | USD 6.11 | USD 62,628 | SEC filing ↗ |
| 2026-06-30 | Thompson Peter A. | Sale (S) | Common Stock | 115,844 | USD 45.50 | USD 5,270,902 | SEC filing ↗ |
| 2026-06-30 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 115,844 | USD 45.50 | USD 5,270,902 | SEC filing ↗ |
| 2026-05-27 | Thompson Peter A. | Sale (S) | Common Stock | 101 | USD 44.49 | USD 4,493 | SEC filing ↗ |
| 2026-05-27 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 101 | USD 44.49 | USD 4,493 | SEC filing ↗ |
| 2026-05-11 | Thompson Peter A. | Sale (S) | Common Stock | 184,639 | USD 46.22 | USD 8,534,015 | SEC filing ↗ |
| 2026-05-11 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 184,639 | USD 46.22 | USD 8,534,015 | SEC filing ↗ |
| 2026-05-08 | Thompson Peter A. | Sale (S) | Common Stock | 59,767 | USD 44.58 | USD 2,664,413 | SEC filing ↗ |
| 2026-05-08 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 59,767 | USD 44.58 | USD 2,664,413 | SEC filing ↗ |
| 2026-05-07 | Thompson Peter A. | Sale (S) | Common Stock | 48,546 | USD 44.61 | USD 2,165,637 | SEC filing ↗ |
| 2026-05-07 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 48,546 | USD 44.61 | USD 2,165,637 | SEC filing ↗ |
| 2026-04-18 | Thompson Peter A. | Sale (S) | Common Stock | 2,948 | USD 44.52 | USD 131,245 | SEC filing ↗ |
| 2026-04-18 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 2,948 | USD 44.52 | USD 131,245 | SEC filing ↗ |
| 2026-04-17 | Thompson Peter A. | Sale (S) | Common Stock | 52,397 | USD 44.68 | USD 2,341,098 | SEC filing ↗ |
| 2026-04-17 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 52,397 | USD 44.68 | USD 2,341,098 | SEC filing ↗ |
| 2026-04-16 | Thompson Peter A. | Sale (S) | Common Stock | 226,906 | USD 45.34 | USD 10,287,918 | SEC filing ↗ |
| 2026-04-16 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 226,906 | USD 45.34 | USD 10,287,918 | SEC filing ↗ |
| 2026-04-15 | Thompson Peter A. | Sale (S) | Common Stock | 235,863 | USD 44.64 | USD 10,528,924 | SEC filing ↗ |
| 2026-04-15 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 235,863 | USD 44.64 | USD 10,528,924 | SEC filing ↗ |
| 2026-04-14 | Thompson Peter A. | Sale (S) | Common Stock | 47,814 | USD 44.51 | USD 2,128,201 | SEC filing ↗ |
| 2026-04-14 | ORBIMED ADVISORS LLC; OrbiMed Capital GP VIII LLC | Sale (S) | Common Stock | 47,814 | USD 44.51 | USD 2,128,201 | SEC filing ↗ |
| 2026-03-05 | Fitzpatrick Jennifer | Sale (S) | Common Stock | 10,250 | USD 33.86 | USD 347,065 | SEC filing ↗ |
Multiple price lines in one filing are grouped and share-weighted. Price and value are blank when a grouped filing line lacks price evidence.
Snapshot & identity
| Snapshot date | 2026-10-18 |
|---|---|
| Ranking version | US-v1.2 |
| Data quality | PASS ELIGIBLE · — |
| Ticker | SION |
| CIK | 0002036042 |
| Sector | Healthcare |
| Industry | Biotechnology Yahoo Finance |
| SEC SIC | 2834 Pharmaceutical Preparations |
| Exchange | Nasdaq |
Data coverage
| Local Form 4 history | 201 transaction lines from 2025-02-10 to 2026-09-17 8 P purchase lines · 160 S sale lines · 33 other lines |
|---|---|
| SEC company submissions | Open SEC filings ↗ |
Local ledger as of 2026-10-18. Mapping status is an audit field and does not erase SEC filing evidence.