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US INSIDER PROFILE · NON-SCORING RESEARCH

Baker Brothers Life Sciences LP

10% Owner | Director

Identity: SEC reporting-owner CIK · Reporting-owner CIK: 0001363364

Purchase history

Companies traded
5
Purchases · 12M
5
Purchases · 24M
10
Average purchase
$52.5M
Median purchase
$36.0M
Gross purchase value
$525.5M

Companies: BICYCLE THERAPEUTICS PLC | Immunocore Holdings plc | Kodiak Sciences Inc. | Kymera Therapeutics, Inc. | MADRIGAL PHARMACEUTICALS, INC.

10 SEC accession(s) · 10 joint-owner event(s). Values are reported Form 4 transaction values in USD.

Qualifying purchase disclosures

PublishedCompanyTickerRoleReported valueSEC source
2026-09-30Kodiak Sciences Inc.KODDirector | 10% Owner$63.4MOpen filing
2026-09-30Kodiak Sciences Inc.KODDirector | 10% Owner$35.0MOpen filing
2026-09-30Kodiak Sciences Inc.KODDirector | 10% Owner$58.6MOpen filing
2025-12-19Kodiak Sciences Inc.KODDirector | 10% Owner$60.0MOpen filing
2025-12-11Kymera Therapeutics, Inc.KYMRDirector | 10% Owner$172.5MOpen filing
2025-08-20MADRIGAL PHARMACEUTICALS, INC.MDGLDirector$25.0MOpen filing
2025-08-20MADRIGAL PHARMACEUTICALS, INC.MDGLDirector$36.9MOpen filing
2025-06-30Kymera Therapeutics, Inc.KYMRDirector$28.8MOpen filing
2025-03-19Immunocore Holdings plcIMCRDirector$24.0MOpen filing
2024-12-17BICYCLE THERAPEUTICS PLCBCYCDirector | 10% Owner$21.2MOpen filing

Post-purchase outcomes

Excess return = stock return − S&P 500 ETF (SPY adjusted close) return. Returns start on the first shared trading session on or after publication.

PeriodCompleted eventsPrice coverageHit rateMedian excess returnAverage excess returnWorst excess return
5D5Developing50.0% (5/10)20.0% (1/5)-5.8%-2.1%-5.8%
20D2Small Sample28.6% (2/7)50.0% (1/2)-4.5%-4.5%-11.1%
60D2Small Sample28.6% (2/7)0.0% (0/2)-19.8%-19.8%-29.9%
120D2Small Sample28.6% (2/7)50.0% (1/2)-11.7%-11.7%-43.2%

Research patterns

First purchase in 12M
1/6
Large purchase ≥ $100k
10/10
Cluster buying · 15D
10/10
Buying the dip
1/5

Routine / opportunistic: Not classifiable. These labels never affect the score or ranking.

Small samples remain visible but are not scored. This research enrichment never affects US-v1.1.